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1

A family of multicyclic indolosesquiterpenes from a bacterial endophyte

Ding, Ling, Maier, Armin, Fiebig, Heinz-Herbert, Lin, Wen-Han, Hertweck, Christian

Journal:

Organic & Biomolecular Chemistry

Year:

2011

Language:

english

File:

PDF, 201 KB

english, 2011

2

Pharmacogenomics of cantharidin in tumor cells

Kadioglu, Onat, Kermani, Navid Salehi, Kelter, Gerhard, Schumacher, Udo, Fiebig, Heinz-Herbert, Greten, Henry Johannes, Efferth, Thomas

Journal:

Biochemical Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.95 MB

english, 2014

3

N-Heterocyclic carbenes derived from imidazo-[1,5- a ]pyridines related to natural products: synthesis, structure and potential biological activity of some corresponding gold(I) and silver(I) complexes

Mihorianu, Monica, Franz, M Heiko, Jones, Peter G, Freytag, Matthias, Kelter, Gerhard, Fiebig, Heinz-Herbert, Tamm, Matthias, Neda, Ion

Journal:

Applied Organometallic Chemistry

Year:

2016

Language:

english

File:

PDF, 1.31 MB

english, 2016

4

ChemInform Abstract: Xiamycin (I), a Pentacyclic Indolosesquiterpene with Selective anti-HIV Activity from a Bacterial Mangrove Endophyte.

Ling Ding, Jan Muench, Helmar Goerls, Armin Maier, Heinz-Herbert Fiebig, Wen-Han Lin, Christian Hertweck

Journal:

Year:

2011

File:

PDF, 20 KB

2011

5

Potential Cancer Chemopreventive in Vitro Activities of Monomeric Xanthone Derivatives from the Marine Algicolous Fungus Monodictys putredinis #

Krick, Anja, Kehraus, Stefan, Gerhäuser, Clarissa, Klimo, Karin, Nieger, Martin, Maier, Armin, Fiebig, Heinz-Herbert, Atodiresei, Iuliana, Raabe, Gerhard, Fleischhauer, Jörg, König, Gabriele M.

Journal:

Journal of Natural Products

Year:

2007

Language:

english

File:

PDF, 176 KB

english, 2007

6

Divergolides A–D from a Mangrove Endophyte Reveal an Unparalleled Plasticity in ansa-Macrolide Biosynthesis

Dr. Ling Ding, Dr. Armin Maier, Prof. Dr. Heinz-Herbert Fiebig, Dr. Helmar Görls, Prof. Dr. Wen-Han Lin, Dr. Gundela Peschel, Prof. Dr. Christian Hertweck

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 459 KB

english, 2011

7

Novel inhibitors of epidermal growth factor receptor: (4-(Arylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)(1H-indol-2-yl)methanones and (1H-indol-2-yl)(4-(phenylamino)thieno[2,3-d]pyrimidin-6-yl)methanones

Thomas Beckers, Andreas Sellmer, Emerich Eichhorn, Herwig Pongratz, Christoph Schächtele, Frank Totzke, Gerhard Kelter, Rebekka Krumbach, Heinz-Herbert Fiebig, Frank-D. Böhmer, Siavosh Mahboobi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.30 MB

english, 2012

8

Kandenols A–E, Eudesmenes from an Endophytic Streptomyces sp. of the Mangrove Tree Kandelia candel

Ding, Ling, Maier, Armin, Fiebig, Heinz-Herbert, Lin, Wen-Han, Peschel, Gundela, Hertweck, Christian

Journal:

Journal of Natural Products

Year:

2012

Language:

english

File:

PDF, 813 KB

english, 2012

9

Anticancer activity of new depsipeptide compound isolated from an endophytic fungus

Verekar, Shilpa Amit, Mishra, Prabhu Dutt, Sreekumar, Eyyammadichiyil Sankaranarayanan, Deshmukh, Sunil Kumar, Fiebig, Heinz-Herbert, Kelter, Gerhard, Maier, Armin

Journal:

The Journal of Antibiotics

Year:

2014

Language:

english

File:

PDF, 287 KB

english, 2014

10

Xiamycin, a pentacyclic indolosesquiterpene with selective anti-HIV activity from a bacterial mangrove endophyte

Ling Ding, Jan Münch, Helmar Goerls, Armin Maier, Heinz-Herbert Fiebig, Wen-Han Lin, Christian Hertweck

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 402 KB

english, 2010

11

Divergolides A–D from a Mangrove Endophyte Reveal an Unparalleled Plasticity in ansa-Macrolide Biosynthesis

Dr. Ling Ding, Dr. Armin Maier, Prof. Dr. Heinz-Herbert Fiebig, Dr. Helmar Görls, Prof. Dr. Wen-Han Lin, Dr. Gundela Peschel, Prof. Dr. Christian Hertweck

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 471 KB

english, 2011

12

Chimerically designed HDAC- and tyrosine kinase inhibitors. A series of erlotinib hybrids as dual-selective inhibitors of EGFR, HER2 and histone deacetylases

Beckers, Thomas, Mahboobi, Siavosh, Sellmer, Andreas, Winkler, Matthias, Eichhorn, Emerich, Pongratz, Herwig, Maier, Thomas, Ciossek, Thomas, Baer, Thomas, Kelter, Gerhard, Fiebig, Heinz-Herbert, Schm

Journal:

Year:

2012

Language:

english

File:

PDF, 488 KB

english, 2012

13

Epoxyphomalin A and B, Prenylated Polyketides with Potent Cytotoxicity from the Marine-Derived Fungus Phoma sp.

Mohamed, Ietidal E., Gross, Harald, Pontius, Alexander, Kehraus, Stefan, Krick, Anja, Kelter, Gerhard, Maier, Armin, Fiebig, Heinz-Herbert, König, Gabriele M.

Journal:

Organic Letters

Year:

2009

Language:

english

File:

PDF, 122 KB

english, 2009

14

ChemInform Abstract: Divergolides A—D from a Mangrove Endophyte Reveal an Unparalleled Plasticity in ansa-Macrolide Biosynthesis.

Ling Ding, Armin Maier, Heinz-Herbert Fiebig, Helmar Goerls, Wen-Han Lin, Gundela Peschel, Christian Hertweck

Journal:

Year:

2011

File:

PDF, 25 KB

2011

15

ChemInform Abstract: Epoxyphomalin A (I) and B (II), Prenylated Polyketides with Potent Cytotoxicity from the Marine-Derived Fungus Phoma sp.

Ietidal E. Mohamed, Harald Gross, Alexander Pontius, Stefan Kehraus, Anja Krick, Gerhard Kelter, Armin Maier, Heinz-Herbert Fiebig, Gabriele M. Koenig

Journal:

Year:

2010

File:

PDF, 21 KB

2010

16

Bacaryolanes A–C, Rare Bacterial Caryolanes from a Mangrove Endophyte

Ding, Ling, Goerls, Helmar, Dornblut, Katharina, Lin, Wenhan, Maier, Armin, Fiebig, Heinz-Herbert, Hertweck, Christian

Journal:

Journal of Natural Products

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

17

Palladium(II) and platinum(II) complexes of (1R,2R)-(−)-1,2-diaminocyclohexane (DACH) with various carboxylato ligands and their cytotoxicity evaluation

Talal A.K. Al-Allaf, Luay J. Rashan, Gerhard Ketler, Heinz-Herbert Fiebig, Amar H. Al-Dujaili

Journal:

Applied Organometallic Chemistry

Year:

2009

Language:

english

File:

PDF, 144 KB

english, 2009

18

Genotyping of NAD(P)H:quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mitomycin C chemotherapy in vivo

Roger M. Phillips, Angelika M. Burger, Heinz-Herbert Fiebig, John A. Double

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 93 KB

english, 2001

19

Absence of Tumor Growth Stimulation in a Panel of 26 Human Tumor Cell Lines by Mistletoe (Viscum album L.) Extracts Iscador in vitro

Kelter, Gerhard, Fiebig, Heinz-Herbert

Journal:

Arzneimittelforschung

Year:

2011

Language:

english

File:

PDF, 363 KB

english, 2011

20

Hygrobafilomycin, a cytotoxic and antifungal macrolide bearing a unique monoalkylmaleic anhydride moiety, from Streptomyces varsoviensis

Tchize Ndejouong, Basile Le S, Sattler, Isabel, Maier, Armin, Kelter, Gerhard, Menzel, Klaus-Dieter, Fiebig, Heinz-Herbert, Hertweck, Christian

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 324 KB

english, 2010

21

Synthesis, topoisomerase-targeting activity and growth inhibition of lycobetaine analogs

Baechler, Simone A., Fehr, Markus, Habermeyer, Michael, Hofmann, Andreas, Merz, Karl-Heinz, Fiebig, Heinz-Herbert, Marko, Doris, Eisenbrand, Gerhard

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 903 KB

english, 2013

22

Parimycin: Isolation and Structure Elucidation of a Novel Cytotoxic 2,3-Dihydroquinizarin Analogue of .GAMMA.-Indomycinone from a Marine Streptomycete Isolate.

MASKEY, RAJENDRA P., HELMKE, ELISABETH, FIEBIG, HEINZ-HERBERT, LAATSCH, HARTMUT

Journal:

The Journal of Antibiotics

Year:

2002

Language:

english

File:

PDF, 686 KB

english, 2002

23

A Novel β-Amino Acid in Cytotoxic Peptides from the Cyanobacterium Tychonema sp.

Christian Mehner, Daniela Müller, Anja Krick, Stefan Kehraus, Reik Löser, Michael Gütschow, Armin Maier, Heinz-Herbert Fiebig, Reto Brun, Gabriele M. König

Journal:

European Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 198 KB

english, 2008

24

Effects of a three-drug antineoplastic protocol of wound healing in rats: A biomechanical and histologic study on gastrointestinal anastomoses and laparotomy wounds

Dr. Richard Salm, Bernd Wullich, Günter Kiefer, Heinz-Herbert Fiebig, Eduard Heinrich Farthmann

Journal:

Journal of Surgical Oncology

Year:

1991

Language:

english

File:

PDF, 662 KB

english, 1991

25

[Au 2 (phen 2Me ) 2 (μ - O) 2 ](PF 6 ) 2 , a Novel Dinuclear Gold(III) Complex Showing Excellent Antiproliferative Properties

Cinellu, Maria A., Maiore, Laura, Manassero, Mario, Casini, Angela, Arca, Massimiliano, Fiebig, Heinz-Herbert, Kelter, Gerhard, Michelucci, Elena, Pieraccini, Giuseppe, Gabbiani, Chiara, Messori, Luig

Journal:

ACS Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1011 KB

english, 2010

26

Glycoside conjugation in microsomes from hepatic and renal carcinoma of man

Heidrun Matern, Heinz-Herbert Fiebig, Siegfried Matern

Journal:

Year:

1987

Language:

english

File:

PDF, 727 KB

english, 1987

27

Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models

Victoria Smith, Edward A. Sausville, Richard F. Camalier, Heinz-Herbert Fiebig, Angelika M. Burger

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 507 KB

english, 2005

28

Microarrays of 41 Human Tumor Cell Lines for the Characterization of New Molecular Targets: Expression Patterns of Cathepsin B and the Transferrin Receptor

Wirth, Gregory J., Schandelmaier, Kathrin, Smith, Victoria, Burger, Angelika M., Fiebig, Heinz-Herbert

Journal:

Year:

2006

Language:

english

File:

PDF, 468 KB

english, 2006

29

In-vitro anti-tumor activity studies of bridged and unbridged benzyl-substituted titanocenes

Kelter, Gerhard, Sweeney, Nigel J., Strohfeldt, Katja, Fiebig, Heinz-Herbert, Tacke, Matthias

Journal:

Anti-Cancer Drugs

Year:

2005

Language:

english

File:

PDF, 122 KB

english, 2005

30

Synthesis and antineoplastic activity of CNC-cysteamine and related compounds

Wei-ci Tang, Johannes Schmid, Heinz-Herbert Fiebig, Gerhard Eisenbrand

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1986

Language:

english

File:

PDF, 747 KB

english, 1986

31

Marine Bacteria. Part 20. Parimycin: Isolation and Structure Elucidation of a Novel Cytotoxic 2,3-Dihydroquinizarin. Analogue of γ-Indomycinone from a Marine Streptomycete Isolate.

Rajendra P. Maskey, Elisabeth Helmke, Heinz-Herbert Fiebig, Hartmut Laatsch

Journal:

Year:

2003

File:

PDF, 8 KB

2003

32

Mechanistic studies on two dinuclear organogold(iii) compounds showing appreciable antiproliferative properties and a high redox stability

Gabbiani, Chiara, Casini, Angela, Kelter, Gerhard, Cocco, Fabio, Cinellu, Maria Agostina, Fiebig, Heinz-Herbert, Messori, Luigi

Journal:

Year:

2011

Language:

english

File:

PDF, 1.91 MB

english, 2011

33

Cytotoxic Bastadin 24 from the Australian Sponge Ianthella quadrangulata ⊥

Greve, Hendrik, Kehraus, Stefan, Krick, Anja, Kelter, Gerhard, Maier, Armin, Fiebig, Heinz-Herbert, Wright, Anthony D., König, Gabriele M.

Journal:

Journal of Natural Products

Year:

2008

Language:

english

File:

PDF, 85 KB

english, 2008

34

Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin

Carbone, Anna, Parrino, Barbara, Barraja, Paola, Spanò, Virginia, Cirrincione, Girolamo, Diana, Patrizia, Maier, Armin, Kelter, Gerhard, Fiebig, Heinz-Herbert

Journal:

Year:

2013

Language:

english

File:

PDF, 544 KB

english, 2013

35

N-heterocyclic carbenes (NHC) with 1,2,4-oxadiazole-substituents related to natural products: Synthesis, structure and potential antitumor activity of some corresponding gold(I) and silver(I) complexes

Maftei, Catalin V., Fodor, Elena, Jones, Peter G., Freytag, Matthias, Franz, M. Heiko, Kelter, Gerhard, Fiebig, Heinz-Herbert, Tamm, Matthias, Neda, Ion

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.56 MB

english, 2015

36

Total synthesis and cytotoxicity of the marine natural product malevamide D and a photoreactive analog

Telle, Werner, Kelter, Gerhard, Fiebig, Heinz-Herbert, Jones, Peter G, Lindel, Thomas

Journal:

Beilstein Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 770 KB

english, 2014

37

ChemInform Abstract: Synthesis and Cytotoxicity of a Diazirine-Based Photopsammaplin.

Hentschel, Fabia, Raimer, Bjoern, Kelter, Gerhard, Fiebig, Heinz-Herbert, Sasse, Florenz, Lindel, Thomas

Journal:

Year:

2015

File:

PDF, 14 KB

2015

38

Correlation of drug response in patients and in the clonogenic assay with solid human tumour xenografts

Scholz, Catherine C., Berger, Dietmar P., Winterhalter, Bernd R., Henβ, Hartmut, Fiebig, Heinz-Herbert

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1990

Language:

english

File:

PDF, 649 KB

english, 1990

39

Trifluoromethylpyridine-Substituted N -Heterocyclic Carbenes Related to Natural Products: Synthesis, Structure, and Potential Antitumor Activity of some Corresponding Gold(I), Rhodium(I), and Iridium(I) Complexes

Maftei, Elena, Maftei, Catalin V., Jones, Peter G., Freytag, Matthias, Franz, M. Heiko, Kelter, Gerhard, Fiebig, Heinz-Herbert, Tamm, Matthias, Neda, Ion

Journal:

Helvetica Chimica Acta

Year:

2016

Language:

english

File:

PDF, 2.15 MB

english, 2016

40

2-benzoxazolyl and 2-benzimidazolyl hydrazones derived from 2-acetylpyridine: A novel class of antitumor agents

Johnny Easmon, Gerhard Puerstinger, Thomas Roth, Heinz-Herbert Fiebig, Marcel Jenny, Walter Jaeger, Gottfried Heinisch, Johann Hofmann

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 201 KB

english, 2001

41

Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study

Angela Casini, Gerhard Kelter, Chiara Gabbiani, Maria Agostina Cinellu, Giovanni Minghetti, Dolores Fregona, Heinz-Herbert Fiebig, Luigi Messori

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2009

Language:

english

File:

PDF, 498 KB

english, 2009

42

In vitro and in vivo evaluation of US-NCI compounds in human tumor xenografts

Fiebig, Heinz-Herbert, Berger, Dietmar P., Winterhalter, Bernd R., Plowman, Jacqueline

Journal:

Cancer Treatment Reviews

Year:

1990

Language:

english

File:

PDF, 528 KB

english, 1990

43

ChemInform Abstract: Hygrobafilomycin, a Cytotoxic and Antifungal Macrolide Bearing a Unique Monoalkylmaleic Anhydride Moiety, from Streptomyces varsoviensis.

Basile Le S. Tchize Ndejouong, Isabel Sattler, Armin Maier, Gerhard Kelter, Klaus-Dieter Menzel, Heinz-Herbert Fiebig, Christian Hertweck

Journal:

Year:

2010

File:

PDF, 18 KB

2010

44

Preclinical activity off hepsulfam and busulfan in solid human tumor xenografts and human bone marrow

Berger, Dietmar P, Winterhalter, Bernd R, Dengler, Wolfgang A, Fiebig, Heinz-Herbert

Journal:

Anti-Cancer Drugs

Year:

1992

File:

PDF, 631 KB

1992

45

Design and Optimization of 20-O-Linked Camptothecin Glycoconjugates as Anticancer Agents

Lerchen, Hans-Georg, Baumgarten, Joerg, von dem Bruch, Karsten, Lehmann, Thomas E., Sperzel, Michael, Kempka, Grazyna, Fiebig, Heinz-Herbert

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 207 KB

english, 2001

46

Molecular Editing and Assessment of the Cytotoxic Properties of Iejimalide and Progeny

Dr. Julien Gagnepain, Dr. Emilie Moulin, Dr. Cristina Nevado, Dr. Mario Waser, Dr. Armin Maier, Dr. Gerhard Kelter, Prof. Heinz-Herbert Fiebig, Prof. Alois Fürstner

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

47

Apralactone A and a New Stereochemical Class of Curvularins from the Marine Fungus Curvularia sp.

Hendrik Greve, Peter J. Schupp, Ekaterina Eguereva, Stefan Kehraus, Gerhard Kelter, Armin Maier, Heinz-Herbert Fiebig, Gabriele M. König

Journal:

European Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 181 KB

english, 2008

48

Role of Transferrin Receptor and the ABC Transporters ABCB6 and ABCB7 for Resistance and Differentiation of Tumor Cells towards Artesunate

Kelter, Gerhard, Steinbach, Daniel, Konkimalla, Venkata Badireenath, Tahara, Tsuyoshi, Taketani, Shigeru, Fiebig, Heinz-Herbert, Efferth, Thomas, Blagosklonny, Mikhail

Journal:

Year:

2007

Language:

english

File:

PDF, 196 KB

english, 2007

49

Pharmacokinetics and antitumor activity of vincristine entrapped in vesicular phospholipid gels

Güthlein, Frank, Burger, Angelika M, Brandl, Martin, Fiebig, Heinz-Herbert, Schubert, Rolf, Unger, Clemens, Massing, Ulrich

Journal:

Anti-Cancer Drugs

Year:

2002

Language:

english

File:

PDF, 141 KB

english, 2002

50

Studies on the constituents of Helleborus purpurascens: analysis and biological activity of the aqueous and organic extracts

Franz, M. Heiko, Birzoi, Roxana, Maftei, Catalin-Vasile, Maftei, Elena, Kelter, Gerhard, Fiebig, Heinz-Herbert, Neda, Ion

Journal:

Year:

2017

Language:

english

File:

PDF, 2.74 MB

english, 2017

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